Epidemiology of Childhood Brain Tumors

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Epidemiology of childhood brain tumors.

BACKGROUND Brain tumors comprise more than 20% of all childhood malignancies, and constitute the greatest number of solid pediatric cancers. Incidence rates reported have varied from 2.4 to 3.5/100,000 children, reflecting the impact of modern imaging techniques, the application of diverse investigative methodologies, and the accessibility of the community to health care. METHODS Material fro...

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Epidemiology of brain tumors in childhood--a review.

Malignant brain tumors are the leading cause of cancer death among children and the second most common type of pediatric cancer. Despite several decades of epidemiologic investigation, the etiology of childhood brain tumors (CBT) is still largely unknown. A few genetic syndromes and ionizing radiation are established risk factors. Many environmental exposures and infectious agents have been sus...

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Epidemiology of brain tumors.

Brain tumors seemed to have increased in incidence over the past 30 years, but the rise probably results from use of new neuroimaging techniques. Treatments have not improved prognosis for rapidly fatal brain tumors. Established brain tumor risk factors (exposure to ionizing radiation, rare mutations of penetrant genes, and familial history) explain only a small proportion of brain tumors, and ...

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Childhood Brain Tumors

Brain cancer is one of the most prevalent childhood cancers in the United States and Canada, second only to leukemia [1, 2]. The overall incidence of childhood brain tumors, the most common solid tumor in children, rose from 2.3 cases per 100,000 in 1975 to 3.0 cases per 100,000 in 1998 in the United States [1]. Similar rates were also seen in Canada [2]. One concern is that the elevated risk o...

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Childhood Brain Tumors

Central nervous system (CNS) cancers are the second most frequent malignancy in childhood and the most common solid tumor in this age group. In recent years, significant advances in surgery, radiotherapy, and chemotherapy have favorably impacted survival for children with these tumors. However, a significant proportion of patients with CNS tumors suffer progress disease despite such treatment. ...

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ژورنال

عنوان ژورنال: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

سال: 1996

ISSN: 0317-1671,2057-0155

DOI: 10.1017/s031716710003883x